Journal article
Phytochemical Investigation of the Constituents Derived from the Australian Plant Macropidia fuliginosa
R Brkljača, JM White, S Urban
Journal of Natural Products | Published : 2015
Abstract
A phytochemical study of the flowers and bulbs derived from the Australian plant Macropidia fuliginosa, involving hyphenated spectroscopic methodologies (HPLC-NMR and HPLC-MS), together with conventional isolation strategies, resulted in the identification of 16 constituents (1, 2, 4-17) representative of six different structural classes. Six new compounds (12-17) were identified from the bulbs of the plant. The isolated compounds were assessed for antimicrobial activity, and compound 8 was found to be more potent against P. aeruginosa than ampicillin. (Chemical Equation Presented).
Grants
Funding Acknowledgements
The Marine and Terrestrial Natural Product (MATNAP) research group would like to thank Mrs. N. Thurbon (School of Applied Sciences (Discipline of Biotechnology and Biological Sciences), Science Engineering and Health, RMIT University) for providing access to the microorganisms to conduct the antimicrobial assays and for her invaluable technical support; Ms. S. Duck (School of Chemistry, Faculty of Science, Monash University) for conducting the HRMS analyses along with access to the HPLC-MS instrument; and Dr. J. Niere for NMR discussions and guidance. R.B. would also like to acknowledge his Australian Postgraduate Award (APA) scholarship that has supported his Ph.D. studies.